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Preface
Introduction
Perioperative Pain Management- Introduction
References
Foundations
General Principles of Perioperative Pain Management
Introduction
Contemporary Principles of Perioperative Pain Management
Types of Pain
Neurophysiology of Pain
Transduction
Transmission
Modulation
Perception
Pain Assessment
Treatment of Perioperative Pain
Local Anesthetics
Non-opioid Pharmacologic Therapies
Opioid and Opiate Therapies
Non-pharmacologic Therapies
Treatment Summary
Role of Pain Management in ERAS
Emerging Therapies
Peripheral Nerve Stimulation
Cryoneurolysis
Oliceridine—Biased Ligand
Transient Receptor Potential Vanilloid 1 Channel Agonists
Extended-Release Local Anesthetic Formulations
Local Anesthetic Adjuvants
Summary
Key Takeaways of Chapter
References
Patient/Surgical Risk Factors for Chronic Pain and Opioid Dependency
Introduction
Chronic Post-surgical Pain
CPSP Risk Factors
CPSP Prevention