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Migraine Management covers the effective treatment of migraines, including different subtypes of migraines in different patient populations. The classification and diagnostic criteria of common and uncommon subtypes of migraine is explored in detail, including childhood variants. An in-depth analysis of the pharmacology of acute and prophylactic agents is presented, along with an evidence-based review of pharmacologic management. This includes recently developed CGRP monoclonal antibodies and non-peptide small molecule CGRP antagonists. Advances in neuromodulatory treatments, both noninvasive and implantable are also critically reviewed. Finally, specific treatment-related issues in pregnancy and lactation and childhood as well as the elderly are covered. Issues related to the diagnosis and management of vestibular migraine and the co-morbid disorder of persistent postural-perceptual dizziness are also explored.
Foreword
Preface
Contributors
Migraine management
Nonspecific analgesics, combination analgesics, and antiemetics
The 5-HT1B and 5-HT1D agonists in acute migraine therapy: Ergotamine, dihydroergotamine, and the triptans
5-HT1F agonists
CGRP receptor antagonists (gepants)
Preventive treatment of migraine: Non-specific oral agents
OnabotulinumtoxinA: Discussion of the evidence for effectiveness of OnabotulinumA and its place in chronic migraine treatment
CGRP monoclonal antibodies and CGRP receptor antagonists (Gepants) in migraine prevention
Nutraceuticals in migraine
Interventional treatments
Biobehavioral treatments of migraine
Physical treatment of migraine
Neuromodulation in migraine
Guidelines
Evidence-based symptomatic treatment of migraine
Evidence-based preventive treatment of migraine
Special cases/situations
Treatment in the emergency department
Special considerations in migraine during pregnancy and lactation
Special considerations in management of migraine in the elderly
Management of medication overuse headache
Outcome measures
Outcome measures for migraine: Measuring the impact of migraine and results of migraine treatment
Diagnosis and treatment of other migraine subtypes
Menstrually associated migraine
Hemiplegic migraine
Migraine with brainstem aura
Retinal migraine
Vestibular migraine and persistent postural perceptual dizziness
Status migrainosus
Persistent aura, visual snow, and other visual symptoms
Migrainous infarction
Migraine in children and adolescents: Assessment and diagnosis
Management of migraine in children and adolescents
Comorbidities of migraine
Psychiatric comorbidities of migraine
Relationship of migraine and other forms of chronic pain
Comorbidities of migraine: Sleep disorders
The evolving concept of multimorbidity and migraine
Future directions
Healthcare disparities encountered by patients with headache disorders and potential mitigation strategies
Emerging and future directions of migraine research and treatment
Index