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This book elucidates the sustainable production of commercially important biomolecules in medicines, food, and beverage processing, through biological systems, including microorganisms, animal cells, plant cells, tissues, enzymes, and in vitro. It discusses promising technologies for the manipulation of cells including, genetic engineering, synthetic biology, genome editing, and metabolic engineering. The initial chapters of the book introduce topics on biomanufacturing, circular economy, strain design and improvement, upstream and downstream processing. The subsequent chapters cover artificial intelligence-assisted production, designer cell factories, biosensors for monitoring biomolecules, different cells factories, biosynthetic pathways, and genome editing approaches for scale-up biomanufacturing. Lastly, the book discusses the opportunities and challenges of implementing biological systems for the production of biomolecules.​This book is a valuable source for students, researchers, scientists, clinicians, stakeholders, policymakers, and practitioners to understand biomanufacturing for the sustainable production of biomolecules.
Strain Design and Optimization Methods for Sustainable Production
Minimal Cells and Genome Minimization:​ Top-Down and Bottom-Up Approaches to Construct Synthetic Cells
Recent Advances in Downstream Processing Deployed in the Treatment of Pharmaceutical Effluents
Microbial Conversion of Waste to Biomolecules
Biosensor for Detecting Biomolecules
Artificial Intelligence-Assisted Production of Biomolecules
Escherichia coli Cell Factory for Synthesis of Biomolecules
Bacillus subtilis Cell Factory
Biomanufacturing for Sustainable Production of Biomolecules: Pseudomonas putida Cell Factory
Cyanobacteria for Marine-Based Biomolecules
Yeast Cell Factory for Production of Biomolecules
Plant Cell Factory for Production of Biomolecules
Genetic Manipulation of Crop for Enhanced Food Quality and Nutrition Toward Sustainable Production
Insect Cell Factory for Production of Biomolecules
Mammalian Cell Culture:​ An Edge to Biopharmaceutica​l Industry
Genome Editing in the Synthetic Biology for Sustainable Production of Biomolecules
Cell-Free Systems for Sustainable Production of Biofuels
Challenges and Opportunities in Biomanufacturing​