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This book is a timely textbook that covers all aspects of neuroendocrine tumors (NET) from epidemiology, pathological classification and evaluation and molecular biology through to diagnostic imaging methods and therapeutic options, including the latest targeted therapies. The various types of NET are individually discussed, including carcinoid tumors, insulinomas, gastrinomas, glucagonomas, VIPomas, somatostatinomas, PPomas, medullary thyroid carcinomas, adrenocortical cancer, pheochromocytomas, paragangliomas and non-functioning pancreatic NETs. The contributing authors are internationally recognized experts who bring a wealth of experience to the subject. This book will be an invaluable source of information for practicing medical oncologists, surgeons, endocrinologists, gastroenterologists and pathologists and also trainees.
Introduction to Neuroendocrine Tumours
History of Neuroendocrine Tumors
Epidemiology of Neuroendocrine Tumors
Molecular Biology of Neuroendocrine Tumors
Genetic Syndromes Associated with Neuroendocrine Tumours
Pathological Evaluation and Classification of Digestive Neuroendocrine Tumours
Circulating Biomarkers in Neuroendocrine Tumours
Cross-Sectional Imaging of Neuroendocrine Tumours
Nuclear Medicine Imaging in Neuroendocrine Tumors
Neuroendocrine Tumors of the Lung
Overview of Gastrointestinal Neuroendocrine Tumours
Insulinoma
Gastrinoma
VIPoma and PPoma
Glucagonoma
Somatostatinoma
Less Common Types of Pancreatic Neuroendocrine Tumors
Nonfunctioning Pancreatic Neuroendocrine Tumors
Gastroenteropancreatic Neuroendocrine Carcinoma
The Multiple Endocrine Neoplasia Syndromes
Thyroid Cancer
Medullary Thyroid Cancer
Diagnosis and Management of Adrenocortical Carcinomas
Pheochromocytoma and Paraganglioma
Surgical Approach in the Treatment of Neuroendocrine Tumours
Liver-Directed Therapies in Neuroendocrine Tumors
Peptide Receptor Radionuclide Therapy
Management of Hormonal Symptoms
Carcinoid Syndrome
Somatostatin Analogs and Interferon in the Treatment of Neuroendocrine Tumors
Chemotherapy
Targeted Therapies
Societies and Guidelines for Neuroendocrine Tumors