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This contributed volume focuses on cardiovascular diseases (CVDs), and explores the ways in which signaling mechanisms at the biochemical, molecular, and cellular levels in the blood vessels (vascular) and heart contribute to the underlying causes of development and progression of the CVDs. This volume covers unique topics such as oxidant signaling in vascular and heart diseases and health, cytoskeletal signaling in vascular health and disease, phospholipase signaling in CVDs, lipid signaling in vascular and myocardial health and diseases, and drug discovery in cellular signaling for cardiovascular diseases.This contributed volume focuses on cardiovascular diseases (CVDs), and explores the ways in which signaling mechanisms at the biochemical, molecular, and cellular levels in the blood vessels (vascular) and heart contribute to the underlying causes of development and progression of the CVDs. This volume covers unique topics such as oxidant signaling in vascular and heart diseases and health, cytoskeletal signaling in vascular health and disease, phospholipase signaling in CVDs, lipid signaling in vascular and myocardial health and diseases, and drug discovery in cellular signaling for cardiovascular diseases.
Cardiac Signaling
Calcium-Dependent Signaling in Cardiac Myocytes
Organization of Ca2  Signaling Microdomains in Cardiac Myocytes
Stress Kinase Signaling in Cardiac Myocytes
Intracellular Cardiac Signaling Pathways Altered by Cancer Therapies
Protein Phosphatase Signaling in Cardiac Myocytes
Metabolic Regulation of Mitochondrial Dynamics and Cardiac Function
NADPH Oxidase System Mediates Cholesterol Secoaldehyde-Induced Oxidative Stress and Cytotoxicity in H9c2 Cardiomyocytes
Lipid Mediators in Cardiovascular Physiology and Disease
Cardiac Inflammasome and Arrhythmia
Myocardial Fibrosis:​ Cell Signaling and In Vitro Modeling
Neural Regulation of Cardiac Rhythm
Vascular Signaling
Mechanisms of Lipoproteins and Reverse Cholesterol Transport in Atherosclerotic Cardiovascular Disease
Atherosclerotic Plaque Regression:​ Future Perspective
Role of Bioactive Lipid, Phosphatidic Acid, in Hypercholesterol​emia Drug-Induced Myotoxicity:​ Statin-Induced Phospholipase D (PLD) Lipid Signaling in Skeletal Muscle Cells
Cell-Cell Communication in the Vascular Endothelium
Lysophosphatidic​ Acid Regulates Endothelial Barrier Integrity
Regulation of Vascular Endothelial Barrier Integrity and Function by Lipid-Derived Mediators
Hyperglycemic Oxoaldehyde (Glyoxal)-Induced Vascular Endothelial Cell Damage Through Oxidative Stress Is Protected by Thiol Iron Chelator, Dimercaptosuccin​ic Acid – Role of Iron in Diabetic Vascular Endothelial Dysfunction