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In light of recent advances in scientific understanding, this textbook provides a comprehensive yet focused guide to anemia, the most common hematologic malady in medicine. This authoritative, clinical resource covers the scientific basis of the many forms of anemia, while offering a practical approach to prognosis, diagnosis and management. Chapters cover a multitude of topics, ranging from the basic components and physiologic functions, to secondary anemias and transfusion therapy. Modern in approach, this text also looks ahead to new and innovative methodologies. With recommended treatment plans and many case studies, this heavily-illustrated book is essential reading for hematologists and oncologists. In providing a pathophysiologic context, it is also of interest to nurse practitioners, physician assistants and medical students in the field. This book provides access to an online version on Cambridge Core, which can be accessed via the code printed on the inside of the cover.​
Preface
The Normal Human RBC
Anemias, Red Cells, and the Essential Elements of Red Cell Homeostasis
Red Cell Production
Red Blood Cell Life Span, Senescence, and Destruction
The Patient with Anemia
The Clinical Approato the Patient with Anemia
Anemia in Children
Specific Forms of Anemia Microcytic Anemias
Iron Deficiency Anemia
Sideroblastic Anemias
The Thalassemia Syndromes
Specific Forms of Anemia Macrocytic Anemias
Macrocytic Anemias - Megaloblastic and Nonmegaloblastic Anemias
Specific Forms of Anemia Hemoglobinopathies
Sickle Cell Syndromes
Structural Hemoglobinopathies
Specific Forms of Anemia Hemolytic Anemias
Autoimmune Hemolytic Anemia
Drug-Induced Hemolytic Anemia
Red Cell Membrane Defects
Malaria
Microangiopathic Hemolytic Anemia
Extrinsic Nonimmune Hemolytic Anemias
Specific Forms of Anemia Hypoplastic Anemias
Acquired Aplastic Anemia and Pure Red Cell Aplasia
Paroxysmal Nocturnal Hemoglobinuria
Congenital Marrow Failure Syndromes
Anemia of Chronic Inflammation
Myelodysplasia
Secondary Anemias
HIV and Anemia
Anemia in the Patient with Cancer
Secondary Anemias Associated with Hematopoietic Stem Cell Transplantation
The Anemia of Aging
Anemia in Pregnancy
Anemias Due to Systemic Diseases
Transfusion Therapy for Anemia
Transfusion Reactions
Management of Anemia
Pharmacologic Therapy of Anemia
Splenectomy - Indications and Consequences
Summary
Anemias
Index