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An understanding of the nervous system at virtually any level of analysis requires an understanding of its basic building block, the neuron. The third edition of From Molecules to Networks provides the solid foundation of the morphological, biochemical, and biophysical properties of nerve cells. In keeping with previous editions, the unique content focus on cellular and molecular neurobiology and related computational neuroscience is maintained and enhanced. All chapters have been thoroughly revised for this third edition to reflect the significant advances of the past five years. The new edition expands on the network aspects of cellular neurobiology by adding new coverage of specific research methods (e.g., patch-clamp electrophysiology, including applications for ion channel function and transmitter release ligand binding structural methods such as x-ray crystallography). Written and edited by leading experts in the field, the third edition completely and comprehensively updates all chapters of this unique textbook and insures that all references to primary research represent the latest results.
Cellular and Molecular
Cellular Components of Nervous Tissue
Subcellular Organization of the Nervous System: Organelles and Their Functions
Energy Metabolism in the Brain
Intracellular Signaling
Regulation of Neuronal Gene Expression and Protein Synthesis
Modeling and Analysis of Intracellular Signaling Pathways
Pharmacology and Biochemistry of Synaptic Transmission: Classical Transmitters
Nonclassic Signaling in the Brain
Connexin and Pannexin Based Channels in the Nervous System: Gap Junctions and More
Neurotransmitter Receptors
Molecular Properties of Ion Channels
Physiology of Ion Channels, Excitable Membranes and Synaptic Transmission
Membrane Potential and Action Potential
Biophysics of Voltage-Gated Ion Channels
Dynamical Properties of Excitable Membranes
Release of Neurotransmitters
Postsynaptic Potentials and Synaptic Integration
Cable Properties and Information Processing in Dendrites
Integration
Synaptic Plasticity
Information Processing in Neural Networks
Learning and Memory: Basic Mechanisms
Molecular Mechanisms of Neurological Disease