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Sex/gender - specific medicine (SGM) is defined as the practice of medicine based on the understanding that biology and social roles are important in men and women for disease prevention, screening, diagnosis, and treatment. Current research demonstrates differences in disease incidence, symptomatology, morbidity, and mortality based on sex and gender. Sex/gender-specific medicine is a fundamental aspect of tailored therapy and precision medicine. Therefore, the variables must be considered in medical education and practice as well as in research models ranging from human participants, animals and cells. Gastroenterology is very big and important division of Internal Medicine, which include esophagus, stomach, small and large intestine, pancreatobiliary tract and liver. Nowadays estrogen is known to play a key role in the prevention of colon cancer and progression of liver cirrhosis and hepatocellular carcinoma, especially in women. This book covers the sex/gender-specific medicine in the area of gastrointestinal (GI) tract in the adults as well as in the pediatrics and in the gut microbiota.
Why Is Sex/Gender-Specific Medicine Needed?
Sex/Gender Differences in the Gastrointestinal Diseases
Metabolism of Sex Hormones
Esophagus
Stomach
Pancreas and Biliary Diseases
Liver
Colon
Gut-Microbiome-Brain Axis
Sex Difference of Gut or Oral Microbiota
Overlap Syndrome of Functional Gastrointestinal Disorders
Sex/Gender Differences in Pediatric Gastrointestinal Diseases
Pharmacokinetics and Pharmacodynamics of Gastrointestinal Drugs
Importance of Education in the Sex/Gender-Specific Medicine and Work-Life Balance of Korean Gastroenterologists