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This book discusses important aspects of the disease, such as treatment, epidemiology, and molecular and cell biology. The information contained herein is important for young researchers as they seek to develop safe and effective treatments for this neglected tropical disease.
Leishmaniasis is a major global health challenge, affecting approximately 12 million of the poorest people in 100 countries. It is a deforming and fatal disease in the visceral form. Therapies for leishmaniasis are numerically restricted, basically consisting of the administration of miltefosine, pentavalent antimonials, amphotericin B, or pentamidine. This is an important vulnerability against therapy efficiency that must be overcome by the scientific community.
Leishmaniasis: Molecular Aspects of Parasite Dimorphic Forms Life Cycle
Protective and Pathogenic Immune Responses to Cutaneous Leishmaniasis
Extracellular Vesicles Released by Leishmania: Impact on Disease Development and Immune System Cells
Treatment of Leishmaniasis
Visceral Leishmaniasis: Asymptomatic Facts
Geographical Distribution of Cutaneous Leishmaniasis and Pathogenesis
Geopolitical and Geospatial Conflicts Affecting Cutaneous Leishmaniasis: Iraqi Cases, 2014-2015
Use of Cell Biology to Identify Cellular Targets in Drug Development Process against Leishmania Sp.
Toward New Antileishmanial Compounds: Molecular Targets for Leishmaniasis Treatment
microRNAs: Are They Important in the Development of Resistance in Leishmaniasis?
Molecular Informatics of Trypanothione Reductase of Leishmania major Reveals Novel Chromen-2-One Analogues as Potential Leishmanicides