Acclaimed screenwriter J. Michael Straczynski begins a run that established him as one of the all-time Spidey greats - joined by the legendary John Romita Jr.! And they kick things off by introducing an enigmatic stranger with a startling secret about Spider-Man's origin! Wrestling with his separation from Mary Jane, Peter goes back to his roots with a new job - science teacher at his old school! But how will Aunt May react when she learns that Peter is really Spider-Man?! Plus: Spidey battles Doctor Octopus, Morlun, Dormammu and more, and teams up with Doctor Strange, Captain America and - Loki?! And as Spidey copes with the horror of 9/11 and relives his heroic career, shocking sins of the past catch up with the wall-crawler!