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This book provides a state-of-the-art overview of the pathogenesis, diagnosis, and treatment of a range of inflammatory, autoimmune, and idiopathic disorders. The opening section covers clinical tools with a particular focus on the role of electromyography and MRI imaging. The second section then presents the differential diagnosis of acquired myopathies based on clinical, electrophysiological, muscle biopsy, and serological criteria, discussing in detail relevant clinical conditions such as including myasthenia gravis, polymyositis, and statin myopathies. The third section examines acute and chronic immune-mediated neuropathies, multifocal motor neuropathies, amyotrophic lateral sclerosis, paraneoplastic diseases, and diabetic polyneuropathy, offering clear guidance on available treatments and descriptions of the latest advances in immunotheraphy, drug therapy, and physiotherapy. This clinically oriented book also includes numerous illustrative figures and contributions by international authors from leading centers.
Diagnostic Tools
Autoantibodies in Neuromuscular Disorders
Electromyography
Imaging of the Muscle in Idiopathic Inflammatory Myopathies
Ultrasound Evaluation of Peripheral Nerves: Evidence, Clinical Application, and Recent Developments
Magnetic Resonance Imaging of the Peripheral Nerve
Clinical Myology Entities
The Spectrum of Inflammatory Myopathies: Dermatomyositis, Polymyositis, Necrotizing Myositis, Anti-synthetase Syndrome-overlap Myositis, and Inclusion-Body Myositis
Necrotizing Autoimmune Myopathy
Statin Myopathy
Myasthenia Gravis
Endocrinological Myopathies
Vitamin D Deficiency in Muscle
Intensive Care Unit-Acquired Weakness
Acquired Immune-Mediated Rippling Muscles With and Without Myasthenia Gravis
Neurogenic Disorders
Idiopathic Chronic Immune-Mediated Neuropathies: Chronic Inflammatory Demyelinating Polyradiculoneuropathy and Multifocal Motor Neuropathy
Immune Neuropathies
Amyotrophic Lateral Sclerosis: Neurochemical Biomarkers
Paraneoplastic Diseases of the Peripheral Nervous System
Diabetic Neuropathy
Infectious Neuropathies
Toxic Neuropathies