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Biologically Active Small Molecules: Modern Applications and Therapeutic Perspectives focuses on small molecules as active pharmacological agents, their pharmacotherapeutically active properties, new approaches in drug discovery using small molecules, and biopharmaceutic approaches for low molecular weight ligands.
Molecules of low mass play a pivotal role in pharmacology because they exhibit multifarious pharmacological effects. Small molecules have become universally popular due to their simple chemistry, easy separation techniques, versatile acceptance for computational studies, large number of places for the substitution of active chemical moieties by well-established synthetic routes with less effort, better quality attributes, and ability to demonstrate numerous biological activities.
This book provides a multidisciplinary approach that delivers the most updated knowledge and advances of some newly developed therapeutically active low molecular weight compounds. It includes chapters that present up-to-date and concise content on the classification, structures, chemical syntheses, medicinal chemistry, pharmacology, biochemical pathways, mechanism of actions, side effects, and adverse effects of small molecule drug discovery. The book covers a broad area by highlighting the advances of inter- and multidisciplinary fields of medicine, chemical sciences, and pharmaceuticals. The flowcharts, figures, illustrations, and diagrams provide important information and will be of great interest for readers.
Bedaquiline: The New Antituberculosis Drug on the Horizon
Plant-Derived Natural Products as Antiglycating Agents
Perspectives of Chalcone-Based Nf-Κβ Inhibitors as Anti-Inflammatory Agents
Coronaviruses: Molecular Modeling and Docking Studies of Potential Drug Candidates Showing Anti-Covid-19 Activity
Perspectives on Local Anesthetics in Medicine
Pharmacotherapeutic Perspectives on Adrenergic Agonists
Therapeutic Perspectives of Adrenergic Antagonists
Skeletal Muscle Relaxants: Concepts and Developments
Nonsteroidal Anti-Inflammatory Drugs: Concepts and Innovations
Biological Databases: Tool for Low Molecular Weight Ligand Discovery Process
High-Throughput Screening Technique: Role in the Drug Discovery of Low Molecular Weight Ligands
Homology Modeling: Applications in the Low Molecular Weight Ligand Designing
Drug Metabolism: Detoxification and Xenobiotic Biotransformation
Drug Interactions: Highlights of Adverse Effects of Low Molecular Weight Ligands
Low Molecular Weight Antioxidant Agents and Model for Their Evaluation