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There is a growing interest in unmet needs for the development of a new discipline in drug discovery and in university education on Polypharmacology. However, there has not been a book with the comprehensive compilation of basic knowledge and advanced methodology on Polypharmacology. This book aims to meet the needs of making Polypharmacology a new sub-discipline of Pharmacology, not only being a hot area of pharmacological research and education but also a new paradigm for drug discovery. It contains the contents covering the entire scope of Polypharmacology including systemic in-depth exposition of basic knowledge, novel concepts, innovative technologies, and translational and clinical applications by showcasing state-of-the-art strategies and step-by-step instructions of cutting-edge methods. The contents of Polypharmacology targets broad readerships including scientists in pharmacology research and drug development, and university teachers and graduates in medical school or school of pharmacy.
Basics of Polypharmacology
Strategies of Polypharmacology
Polypharmacology in Clinical Applications—Anticancer Polypharmacology
Polypharmacology in Clinical Applications: Cardiovascular Polypharmacology
Polypharmacology in Clinical Applications: Metabolic Disease Polypharmacology
Polypharmacology in Clinical Applications: Neurological Polypharmacology
Polypharmacology in Clinical Applications: Respiratory Polypharmacology
Polypharmacology in Clinical Applications: Gastrointestinal Polypharmacology
Polypharmacology in Clinical Applications: Renal Polypharmacology
Polypharmacology in Clinical Applications: Anti-infection Polypharmacology
Polypharmacology in Clinical Applications—Anti-inflammation Polypharmacology
Polypharmacology in Drug Design and Discovery—Basis for Rational Design of Multitarget Drugs
Polypharmacology in Old Drug Rediscovery: Drug Repurposing
Polypharmacology in Predicting Drug Toxicity: Drug Promiscuity
Polypharmacology and Natural Products
Polypharmacology and Polypharmacokinetics
General Process for Rational Design and Discovery of MTDs
General Strategies for Rational Design and Discovery of Multitarget Drugs
Databases for Rational Design and Discovery of Multitarget Drugs
Methods for Rational Design and Discovery of Multitarget Drugs
Exemplary Protocols of Rational Design of Multitarget Drugs